Comfortan®Solution for Injection
Comfortan®Solution for Injection is a veterinary medication used for dogs and cats. It contains methadone, which is a powerful analgesic and tranquilizer. It's typically used for pain relief and as a premedication for general anesthesia
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Indications: Analgesia in dogs and cats, premedication for general anesthesia or neuroleptanalgesia in combination with a neuroleptic drug.
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Contraindications: Should not be used in animals with advanced respiratory failure, severe liver and renal dysfunction, or known hypersensitivity to methadone.
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Special Precautions: Methadone may cause respiratory depression and should be used with caution in animals with impaired respiratory function. Regular monitoring of heart rate and respiratory rate is recommended.
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Pharmacokinetics: Methadone is rapidly absorbed following intramuscular injection, with a high bioavailability. It has a large volume of distribution and is extensively protein-bound.
Key Features
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Active Ingredient: Contains methadone, a potent analgesic and tranquilizer.
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Indications: Used for pain relief in dogs and cats, and as premedication for general anesthesia.
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Administration: Can be administered by intramuscular or intravenous injection.
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Onset and Duration: Rapid onset of action with long-lasting effects.
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Dosage: Specific dosage varies based on the animal's weight and condition; always follow veterinary guidelines.
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Safety Precautions: Regular monitoring of heart rate and respiratory rate is recommended, especially in animals with respiratory, liver, or kidney issues.
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Bioavailability: High bioavailability when injected intramuscularly.
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Metabolism and Excretion: Extensively metabolized in the liver and excreted via urine.
legal category: POM-V (Prescription Only Medicine - Veterinarian) and is classified as a CD (Sch 2) (Controlled Drug, Schedule 2)
CD (Sch 2) (Controlled Drug, Schedule 2): This indicates that Comfortan® is a controlled substance with strict regulations due to its potential for abuse and dependency. It must be stored securely, and records of its use must be meticulously maintained.